ARISE II: Unleashing America’s Research & Innovation Enterprise tackles a broad set of issues
facing the U.S. science and technology community. Although research in science and
engineering is integral to America’s health, security, and economic strength, there are persistent challenges to the vitality of this enterprise. pdf 
ARISE II report available from the American Academy of Arts and Sciences. website
Transdisciplinary and trans-sector research is essential to advance scientific discovery; government funding for scientific research is increasingly uncertain; and support for basic curiosity-driven programs, high-risk science, and young investigators is difficult to secure.
From the American Academy of Arts and Sciences, Cambridge, Massachusetts
Recommendation 1.1 (to academia and government) Develop and foster a massive “knowledge network” that enables investigators from different disciplines to identify opportunities, establish collaborative efforts, and focus disparate expertise and approaches on problems of common interest.